C&L Instruments, Inc.

Celebrating 20 years in business.
 Building solutions and satisfying our customers, one at a time!

C&L Awarded US Patent No. 7,245,368
Sample Chamber for Microscopy
Innovative sample chamber design hold coverslips using a vacuum force.  Coverslips attach leak-free, without breakage and in seconds to create a laminar flow chamber.

C&L Instruments manufactures fluorometers and fluorometer components for  steady-state fluorescence measurements.  We offer complete fluorescence systems for your microscope for photometry measurement.  We also offer cuvette-based fluorometers, illumination sources, photon-counting detectors and numerous handy accessories.  Also be sure to examine our new line of microscope perfusion chambers.
 

New Products 
 

Filter Wheel Synchronization Patent	Coming soon New mini Chamber for 18 mm coverslips	Vacu-CellTM Incubation Chambers

What's New at C&L

• New Mini Series Perfusion chambers are available.   The Mini Series Thin Window chamber forms a 100 micron thick chamber with one body part and two coverslips!

• NEW 3D Interactive Model!

• New C-Mount photomultiplier detectors, Models DPC-BA and DPC-MA provide simple and cost effective photometry.  See them here.

• Incubate coverslips in standard fluorescence cuvettes using our CCH-1 and CCH-2 inserts.  Very nice.

• New FluorMeasure^TM Software allows for:

  • external data acquisition triggering.

  • data synchronization with electrophysiology systems.

  • time-lapse fluorescence measurements.  See details!

• Measure O₂ consumption simultaneously with fluorescence.   Details here.

Browse our web site to learn more about our unique fluorescence systems.

Our fluorometers are:
Versatile. The components of our fluorometer systems are modular.   They can interchangeably connect to a fluorescence microscope, a cuvette accessory, or a surface fluorescence probe.  
Sensitive and have low noise. Our fluorometers are entirely digital. We use end-on photon-counting PMT's for high sensitivity, wide dynamic range and low noise.
Multiwavelength. Select up to eight excitation and eight emission wavelengths for measurement of nearly any fluorescent probe or probe combination.   You can use both excitation and emission wavelength-shift probes (fura-2, BCECF, indo-1, etc.) in several combinations. Our imaging system also supports imaging at eight wavelengths!
Fast.  You can acquire up to eight excitation-emission wavelength pairs in 8 milliseconds (1 KHertz/wavelength pair) with our photometry systems.   Fluorescence ratios (fura-2, indo-1, etc.) can be measured at 0.5 KHertz, continuously (500 ratios/sec).  
Plug and Play. No optical alignment required.  Just plug it in and collect data.
Economical. Our systems offer more, but cost much less.  

Please browse our web site, review our products, see how our systems are integrated and download our specification sheets and software.  Do not hesitate to contact us!   We would be pleased to help you solve your application needs.